ABSTRACT

Damage of the CNS after an SCI (spinal cord injury), stroke or in PD leads to primary deficits and secondary adaptations of the neuronal control of complex, natural movements in movement disorders. The knowledge of the pathophysiology underlying movement disorders can lead to a more precise definition of the specific requirements for the rehabilitation of the affected patients. This is an important aspect since people live longer nowadays and movement disorders have become one of the most rapidly expanding fields in medicine, leading to increasing costs for treatment and rehabilitation. Conversely, the advances in studies of patients with movement disorders allow us a better understanding of movement control in healthy states.