ABSTRACT
The management of the obese diabetic patient
remains a challenge for the clinician (Figure
2.8). Strategies include:
(1) Promoting weight loss, through the use
of lifestyle modifications (hypocaloric
diet and exercise), very-low-calorie diets,
anti-obesity drugs and even, in well-
selected cases, bariatric surgery;
(2) Improving glycaemic control, through a
reduction in insulin resistance (lifestyle
modifications, metformin, insulin
sensitizers such as thiazolidinediones,
benfluorex), a correction of insulinopenia
OBESITY DIABETES
CALORIC INTAKE
INTESTINAL ABSORPTION
LIVER PRODUCTION
Anorectic agents
Intestinal enzyme
inhibitors
Beta-3 agonists?
