Infusional 5-ﬂuorouracil: The bimonthly approach Aimery de Gramont, Christophe Louvet, for the GERCOR (Oncology Multidiscplinary Research Group)

doi:10.3109/9780203213650-53

Chapter

Infusional 5-ﬂuorouracil: The bimonthly approach Aimery de Gramont, Christophe Louvet, for the GERCOR (Oncology Multidiscplinary Research Group)

ABSTRACT

The bimonthly regimen was designed to combine both 5-FU continuous infusion and leucovorin modulation. In addition, a synergism between the administration of 5-FU by bolus and continuous infusion has been demonstrated in vitro.14