ABSTRACT
Numerous epidemiological studies
support the notion that postmenopausal use
of HRT is associated with a 40-60%
reduction in the risk of coronary heart disease
and a 2-4-fold increased risk of venous
thromboembolism, while it has a neutral
effect on the risk of stroke. There is therefore
no simple answer to the question of a possible
protective effect of HRT on the risk of
thrombosis. This chapter will deal with the
epidemiological evidence.