Brain Disease | Therapeutic Strategies and Repair | Oded Abramsky, D.

Book

ABSTRACT

Recent research has unearthed new insights into brain disease. In this volume, leading scientists review the latest experimental and clinical findings on how the central nervous system (CNS) responds to injury. Brain Disease encompasses the mechanisms of CNS disorders, such as multiple sclerosis, Alzheimer's disease, stroke and traumatic brain inju

TABLE OF CONTENTS

part |2 pages

Part 1 Neuroimmunology and immune-mediated demyelination

chapter 1|8 pages

The spectrum of neuroimmunologic diseases

chapter 2|10 pages

Heterogeneity in multiple sclerosis Alastair Compston

chapter 3|8 pages

Microglia and brain macrophages Jack P Antel, Rosanne Seguin

chapter 4|8 pages

Humoral immune response and antibody-mediated brain injury Nicole Kerlero de Rosbo, Avraham Ben-Nun

chapter 5|8 pages

Antibody-mediated remyelination Allan J Bieber, Arthur E Warrington, Virginia Van Keulen, Bogoljub Ciric, Larry R Pease, Moses Rodriguez

chapter 6|6 pages

Apoptosis in multiple sclerosis and experimental autoimmune encephalomyelitis (EAE) Daniel Offen, Ronit Mosberg-Galili, Eldad Melamed

chapter 7|12 pages

Cell migration and adhesion molecules at the blood–brain barrier in experimental autoimmune encephalomyelitis and multiple sclerosis Juan J Archelos, Bernd C Kieseier, Hans-Peter Hartung

chapter 8|6 pages

Matrix metalloproteinases and their inhibitors in brain injury and repair Ariel Miller, Sarah Shapiro, Nitza Lahat, Yanina Galboiz

chapter 9|4 pages

Monitoring progression of multiple sclerosis: p-cresol sulfate is the dominant component of urine Ligong Cao

chapter 10|10 pages

Immunomodulation and therapy in multiple sclerosis Arnon Karni, Karim Makhlouf, Samia J Khoury, Howard L Weiner

chapter 11|8 pages

Immunogene therapy for autoimmune demyelination Roberto Furlan, Pietro L Poliani, Alessandra

chapter 12|6 pages

DNA vaccination for central nervous system autoimmune diseases Nathan Karin

chapter 13|8 pages

Stem cell transplantation for neurological diseases: new hope for disorders of myelin? Tamir Ben-Hur

part |2 pages

Part 2 Infections and lymphoproliferative disorders

chapter 14|20 pages

Viruses in neurological disease Jill R Breen, Donald H Gilden

chapter 15|10 pages

Chronic fatigue syndrome and systemic viral infections: current evidence and recent advances Abhijit Chaudhuri, John Gow, Peter O Behan

chapter 16|6 pages

Bacterial meningitis Hans-Walter Pfister, Uwe Koedel

chapter 17|8 pages

Human prion diseases Amos D Korczyn

chapter 18|10 pages

Neurologic manifestations of lymphoproliferative disorders Tali Siegal

part |2 pages

Part 3 Vascular and traumatic events: Pathogenesis and repair

chapter 19|10 pages

Cerebrovascular disorders: therapeutic strategies and repair Jorge Moncayo Gaete, Julien Bogousslavsky

chapter 20|20 pages

Vasculitis of the nervous system Aksel Siva

chapter 21|8 pages

Brain vasculitis and antiphospholipid syndrome Lubica Rauova, Joab Chapman, Yehuda Shoenfeld

chapter 22|10 pages

Neuronal protection in cerebral ischemia—from lessons of the past to a brighter future Ronen R Leker

chapter 23|8 pages

Immunomodulation—new therapeutic opportunities for stroke Giora Z Feuerstein, Xinkang Wang

chapter 24|6 pages

Toxicity of tumor necrosis factor is enhanced by reactive oxygen species after brain trauma Esther Shohami

chapter 25|6 pages

Protective autoimmunity: is vaccination for neurodegenerative disorders feasible? Michal Schwartz

chapter 26|6 pages

The molecular biology of blood–brain barrier disruption under stress: the potential involvement of acetylcholinesterase Hermona Soreq, Daniela Kaufer, Ilan Shelef, Haim Golan, Oren Tomkins, David Glick, Eli Reichenthal, Alon Friedman

part |2 pages

Part 4 Treatment of epilepsy and paroxysmal syndromes

chapter 27|6 pages

Clinically important interactions involving new antiepileptic drugs Yitzhak Schiller

chapter 28|6 pages

Challenges in monitoring the new antiepileptic drugs Svein I Johannessen, Torbjörn Tomson

chapter 29|6 pages

Aggravation of seizures by antiepileptic drugs: pathophysiology and clinical implications Miri Y Neufeld

chapter 30|8 pages

Management of paroxysmal symptoms in multiple sclerosis Christian Confavreux, Françoise Bouhour, Sandra Vukusic

part |2 pages

Part 5 Degenerative diseases

chapter 31|8 pages

An update on therapy for Parkinson’s disease Sharon Hassin-Baer, Nir Giladi

chapter 32|8 pages

Restoring structure and function of the nigrostriatal system in Parkinson’s disease Olle Lindvall, Peter Hagell

chapter 33|8 pages

Therapeutic of hyperkinetic movement disorders Jose Martin Rabey

chapter 34|8 pages

Molecular events in dopaminergic neurodegeneration and neuroprotection in MPTP model of Parkinson’s disease employing cDNA microarray Silvia Mandel, Edna Grünblatt, Yona Levites, Gila Maor, Moussa BH Youdim

chapter 35|12 pages

Alzheimer’s disease Abdalla Bowirrat, Robert P Friedland, Amos D Korczyn

part |2 pages

Part 6 Nerve and muscle

chapter 36|12 pages

Vasculitic neuropathies Gérard Said

chapter 37|12 pages

Acquired demyelinating neuropathies: molecular mechanisms and novel therapeutical Nicole Schaeren-Wiemers

chapter 38|10 pages

Radiation damage to peripheral nerves Alexander Lossos, Ofer Merimsky

chapter 39|4 pages

Neuropathy due to malignant hematological diseases Austin J Sumner

chapter 40|6 pages

Hereditary inclusion body myopathies: clinical and genetic features Zohar Argov

chapter 41|10 pages

Exercise testing in muscle disease John Vissing

part |2 pages

Part 7 Specific neurological symptoms

chapter 42|6 pages

Disorders of emotional behaviour JP Newman

chapter 43|4 pages

Cognitive and affective disturbances in multiple sclerosis Jürg Kesselring, Ulrike Klement

chapter 44|10 pages

From spinal shock to spasticity

chapter 45|6 pages

Pathophysiology and treatment of fatigue in multiple sclerosis Giancarlo Comi, Letizia Leocani, Bruno Colombo, Paolo Rossi

chapter 46|10 pages

Management of vertigo and vestibular disorders Thomas Brandt

chapter 47|12 pages

Eye movements: supranuclear mechanisms and their disorders Lea Averbuch-Heller

part |2 pages

Part 8 Imaging and clinical neurophysiology

chapter 48|6 pages

The role of radionucleid brain scan and multimodality Isabelle Berry, Pierre Duthil, Frédéric Courbon, Slimane Zerdoud, Monique Bessou, Michel Clanet, Claude Manelfe

chapter 49|10 pages

Imaging brain inflammation Marco Rovaris, Massimo Filippi

chapter 50|12 pages

Advances in neurosonology Michael Hennerici, Stephen Meairs

chapter 51|16 pages

Neurophysiology of inflammatory demyelinating disease Kenneth J Smith