ABSTRACT
The pioneering work of Markee (1948), who autotransplanted rhesus endometrium to the anterior eye chamber, provided insights into the vascular changes which accompany menstruation. More recent studies of perimenstrual dissolution of stromal extracellular matrix, endometrial vasoconstriction, vascular disruption and tissue sloughing have helped to elucidate some of the biological mechanisms underlying Markee’s original observations (review Lockwood and Schatz, 1996).
