ABSTRACT

Epilepsy is a brain disorder affecting 0.5-1.0% of the population, characterized by recurrent seizures. Seizures are the result of excessive discharges of neo-or archi-cortical neurons firing in abnormal synchrony. Seizure symptoms and seizure consequences are determined by the function of the brain region from which the abnormal discharge originates, by the degree of spread to other structures of the brain, and by the quantity and rate of excitatory and inhibitory neurons participating.