ABSTRACT
A review on mammalian proteinases may seem out of place in a book on biochemical protozoology, but, if drugs targetted to parasitic proteinases are to be considered useful in the control of parasitic protozoa in man, then it is essential that the host proteinases are not also inactivated by such drugs. In addition, the known similarities between mammalian and parasitic proteinases suggest that it is likely that techniques used to control the activity of mammalian proteinases will also be applicable to parasitic proteinases. This review therefore concentrates on the control of specific proteolytic activity and attempts to direct the reader to consider methods for controlling the activity of individual proteinases, rather than generally inhibiting proteolysis.
