ABSTRACT

Thirty years ago I trained as a comparative biochemist in the laboratory of Ernest Baldwin and during my 25 years in research I always worked on parasitic organisms. The varied evolutionary origins of the parasitic protozoa and helminths, and their adaptations to parasitism, make studies of their biochemical structures and meta-bolism particularly rewarding. There is a great excitement and satisfaction in successfully carrying out a biochemical study which demonstrates a new enzyme, pathway or structure in a parasitic organism: to add one more piece to the jigsaw, which leads to greater understanding of its complex life-style.