most readily identifiable signs of AIDS. Pictured here is Mark Early, a member of the People with AIDS Coalition (PWAC), in 1986.
Papular lesions or plaques are often found on the hands and feet, whereas larger plaques with nodules frequently occur around the elbows and knees of patients. The plaques and nodules on the legs are often associated with painful edema (swelling). Infiltration of the lymphatic system alters the course and dimension of cutaneous KS and can cause extreme pain, maceration, and ulceration.