ABSTRACT
Dupuytren’s disease is associated with knuckle (Garrod’s) pads, plantar fibromatosis in the feet (Ledderhose’s disease), Peyronie’s disease, diabetes, alcoholism, and epilepsy treated with phenytoin, epanutin or phenobarbitone. It is no more common among smokers. There is a reduced incidence in rheumatoid patients. A history of trauma is not infrequently elicited but it is debatable whether blunt trauma and manual work are causative. It is likely that genetic predisposition is the most important factor and that the other factors determine the age of onset of the disease.
