ABSTRACT

Thrombolytic therapy for stroke with the introduction of tissue plasminogen activator (t-PA) was a boon to stroke physicians, since it meant that morbidity and mortality could be reduced with the optimal use of t-PA. The editor and his well-respected contributors offer the reader their personal perspectives on the evidence-based use of various thrombolytic and anti-thrombotic agents that are available and that can provide successful outcomes. Thrombolytic and Antithrombotic Therapy for Stroke is updated and thoroughly referenced. Everyone working in the casualty/emergency room must read this clearly-written text.

chapter |4 pages

List of Contributors

chapter |2 pages

Preface

chapter 1|12 pages

Thrombosis and therapeutic antidotes: historical aspects

Louis R Caplan Thrombosis takes center stage

chapter 2|8 pages

Antithrombotic drugs: anticoagulants (heparins)

Ángel Chamorro Unfractionated heparin (UFH)

chapter 3|10 pages

Fibrinolytic agents

Roger Lijnen, Nobuo Nagai, and Désiré Collen

chapter 9|18 pages

Aspirin in acute stroke

chapter 11|10 pages

New antithrombotics and their potential use

Patrik Michel Thrombosis and antithrombotics in acute stroke: current knowledge

chapter 13|10 pages

Thrombolytic therapy for acute stroke: the studies

Peter D Schellinger, Jochen B Fiebach, and Peter A Ringleb

chapter 14|10 pages

Complications of thrombolysis

chapter 18|10 pages

Intra-arterial thrombolysis for acute ischemic stroke

Anthony J Furlan and Herman Zeumer Intra-arterial thrombolysis

chapter 19|20 pages

Various combined approaches: present and future

Danilo Toni, Svetlana Lorenzano, Romesh Markus, and Geoffrey Donnan intra-arterial thrombolysis