chapter  10
Dynamics of nuclear lamina assembly and disassembly
ByJos L. V. Broers, Frans C. S. Ramaekers
Pages 17

Since the discovery of nuclear lamins some 20 years ago, functions in nuclear stability and chromatin organization have been suggested for these intermediate filament-type proteins. While initially the nuclear lamina was considered to be a rigid structure, supporting the nuclear membrane, the use of GFP-tagged lamins in studying nuclear lamina behaviour provides us with a growing insight that the lamina is highly flexible (Broers et al., 1999).