ABSTRACT

This chapter gives the student a sense of the importance of the basic knowledge and scientific principles required to understand the manufacturing, formulation, use, and biopharmaceutical aspects of conventional solid dosage forms. It focuses on conventional solid oral dosage forms and divides into three sections: powder and granules, tablets, and capsules. Lozenges are compressed tablets that do not contain a disintegrant. Oral powders generally can be supplied as finely divided powders or effervescent granules. The finely divided powders are suspended or dissolved in water or mixed with soft foods such as applesauce before administration. Dentifrices may be prepared in the form of a bulk powder, generally containing soap or detergent, mild abrasive, and anticariogenic agent. Douche powders are completely soluble and are dissolved in water prior to use as antiseptics or cleansing agents for a body cavity. Insufflations are finely divided powders introduced into body cavities such as the throat.