ABSTRACT
This book focuses on dopamine-mediated regulation of gene expression within the striatum and associated regions of the central nervous system. It is an excellent review of experimental data on interactions between neuronal systems at systemic, cellular, and molecular levels. Each of the chapters, written by the world's leading scientists, provides an understanding of anatomy, neurochemistry, and cellular and molecular effects. Such an understanding sheds light on the pathophysiology of central disorders involving the basal ganglia and leads to new approaches for the treatment of diseases such as Parkinson's disease and schizophrenia, and also addictions to psychostimulants such as cocaine and amphetamines.
TABLE OF CONTENTS
part I|78 pages
Dopamine-Mediated Gene Expression in the Neostriatum
part II|56 pages
Neurotransmitter Interactions Regulating Striatal Gene Expression
part III|62 pages
Persistent Alterations in Gene Expression Involved in Behavioral Adaptations