ABSTRACT
Glutathione (GSH) is the most concentrated intracellular nonprotein thiol. It is an essential element of the oxidoreduction status of many cells. 1 Due to its binding to proteins and by thiol/disulfide exchange, it plays a role in the regulation of enzyme activities. 2 It participates in the cellular defense mechanisms by terminating free-radical mediated chain reactions or by conjugating reactive intermediates of xenobiotics.
