chapter  27
Open conservation surgery for laryngeal cancer
ByVolkert Wreesmann, Jatin Shah, Ian Ganly
Pages 12

INTRODUCTION Cancer of the larynx is a debilitating disease associated with signicant functional morbidity (breathing, speech, swallowing) and mortality. The preferred treatment choice for laryngeal cancer patients provides the optimal balance between disease control prospects and likelihood of treatment-related functional, aesthetic and psychological side effects.1 Total laryngectomy (TL) with or without post-operative radiation treatment (PORT) offers the best chances for cure across all types and stages of laryngeal cancer.2 However, TL is associated with severe functional sequela (Table 27.1), signicant reduction in quality of life (QOL) and low patient acceptance. As such, it is now mostly applied to clinical scenarios in which TL is the sole viable treatment option, such as advanced (T4a) tumour stage, or in cases of locally recurrent disease after radiation treatment. The majority of laryngeal cancers can be treated with more conservative treatment alternatives that provide an improved risk-benet ratio compared to TL.3