ABSTRACT

This important, new reference provides the first , up-to-date, and comprehensive treatmentof the various liquid chromatography (LC) instrumentation for Therapeutic DrugMonitoring (TDM) and toxicology drug assays and reviews the clinical pharmacologyof major classes of drugs and their LC analyses.Written by authoritative contributors who bring many years of personal laboratory/clinical experience to the book, this interdisciplinary work : presents the principlesof TDM, sampling techniques, and various instrumentation topics, including computerinterfacing, mass spectrometry, fluorescence , electrochemical detection, and bloodcollection devices . .. examines six primary classes of drugs, complete with recommendedLC procedures and emphasizing recently introduced drugs and their LC analyses. .. and documents medicolegal guidelines and laboratory management considerations,providing a contemporary assessment of today's laboratory needs.The only practical, current guide available on the subject, Therapeutic Drug Monitoringand Toxicology by Li([uid Chromatography belongs in the personal libraries of clinicaland analytical chemists and biochemists, clinical pharmacologists, clinical toxicologists,clinical pathologists, immunologists, liquid chromatographers, mass spectroscopists, laboratorydirectors, laboratory instrument manufacturers , and medical technologists. Thebook is also vital supplementary reading for advanced undergraduate and graduate-levelclinical chemistry, toxicology, clinical pathology, and liquid chromatography course.

chapter 1|10 pages

Introduction

part I|1 pages

Fundamentals and Current Clinical Instrumentation

chapter 4|10 pages

Sampling Technique

part II|1 pages

II Major Classes of Drugs

chapter 9|32 pages

Antiasthmatics

chapter 10|40 pages

Antibiotics

chapter 11|42 pages

Antidepressants

chapter 12|16 pages

Anticonvulsants

chapter 13|38 pages

Antihypertensives

chapter 14|32 pages

Antiarrhythmics

part III|1 pages

Laboratory Management and Miscellaneous Topics