ABSTRACT

Introduction

Structure of GSH

Free Radicals

GSH as a Putative Neurotransmitter

Glutamate as a Neurotransmitter

Glutamate Receptor Divisions

Ionotropic Glutamate Receptors

Metabotropic Glutamate Receptors

Biological Test Preparation

Structure–Activity Relationship Studies

Initial Studies

Dipeptide Actions

Manipulation of the Thiol Function

GSH Antagonist Development

Future Directions

References