ABSTRACT

A second possibility for the difference in laterality of the amygdala response across these two protocols is the nature of learned material and the type of representation that is evoked. Studies with brain-in.iured patients have shown that the right amygdala may lllodul<lte the fcar response when the aversive properties of the

a R~0649,p=O,31 b H~085.p_00009 Fig, 3. Correlation between SCR and activation strength for amygdala and insular cortex. Con'e!ation between measures of autonomic arousal (difference SCR) and (a) magnitude of amygdalar functional activation and (b) magnitude of insular functional activation. Difference SCR is expressed as mean threat SCR minus mean safe SCR. Regional magnitude of functional activation was obtained by summing the t-values of all significantly active pixels within an ROI for each brain structure for early threat versus early safe trial comparison (p < 0.05).