of of the of f o : In order to examine the co-transmission diagnostic criteria for these specific disorders two major anxiety disorders (i.e. social phobia and anxiety group assignment (i.e. social phobia and panic, social phobia, panic, other anxiety Table 4. Co-morbidity and none). In proportional hazard models (Table which included panic disorder and social phobia, both alcohol dependence (risk ratio 3'01, P 0'0001) and panic disorder (risk ratio = 1-63, P Alcoholism in relatives < 0'01) in the proband independently increased (hazard ratios±95% CI) the risk of alcohol dependence in relatives,

doi:10.4324/9780203825266-33

Chapter

Chapter

In order to examine the co-transmission diagnostic criteria for these specific disorders two major anxiety disorders (i.e. social phobia and anxiety group assignment (i.e. social phobia and panic, social phobia, panic, other anxiety Table 4. Co-morbidity and none). In proportional hazard models (Table which included panic disorder and social phobia, both alcohol dependence (risk ratio 3'01, P 0'0001) and panic disorder (risk ratio = 1-63, P Alcoholism in relatives < 0'01) in the proband independently increased (hazard ratios±95% CI) the risk of alcohol dependence in relatives,

ABSTRACT

FIG. 1. Adjusted odds ratios of levels of alcoholism (abuse/dependence) of relatives from cumulative logit models of alcoholism and anxiety in probands and relatives. The 95% confidence limits are: proband alcohol dependence-relative alcohol dependence (2'2,4'2); proband panic-relative alcohol dependence (1'1,2'2); proband social phobia-relative alcohol dependence (0,7. 1'4); proband alcohol dependence-relative alcohol abuse (l'8-3'1); proband panic-relative alcohol abuse (1'1,1'8); proband social phobia-relative alcohol abuse (0-85, 1'26). For relatives: relative social phobia-alcohol dependence (1'0,2'6); relative panic-relative alcohol dependence (0'1, 2·S) male ~ (1'2. 5'5) female; relative panie~relative alcohol abuse (0'43.2'19) male ~ (1·15-4·06) female; relative social phobia-alcohol abuse (0·99-2·04). Each odds ratio controls for: (1) the other six proband and relative diagnoses shown induding a panic by sex interaction; and (2) proband sex, relative sex, relative age and interview status. (* P < 0·05; ** P < 0-01.)