ABSTRACT
In recent years, accumulating evidence has established the important role of training status in the ability to resist fatigue during high-intensity muscle contractions. Training status reflects the level of adaptation of the different physiological systems to chronic exercise or inactivity. Several studies have shown that different types of training result in distinct adaptations at the structural, metabolic, hormonal, neural and molecular level. Similarly, even a few weeks of inactivity in the form of detraining or immobilisation will decrease fatigue resistance due to both peripheral and central mechanisms.
