chapter  6
18 Pages

A microarray-based screening method for known and novel SNPs

ByEna Wang, Francesco M Marincola

In recent years, matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) has emerged as a powerful tool for genotyping SNPs (17-19). The comprehensive utilization of this approach is, however, hampered by the complexity of the technology, the cost and the limited throughput.