This chapter sets out to discern the influence national culture can have on GIS design. Culture plays a crucial role in all human activity, but is entangled with institutions, disciplines, and our daily lives in perplexing ways. Studies of cultural influence on GIS technology stand to benefit the GIS research and practitioner communities through insights into this frequently down-played area. This research focuses specifically on national culture influences in GIS design, building on prior work in geography, cartography, GIS, information science, and sociology. It employs ethnographic research methods to examine the embedded relationships between national culture and GIS design, comparing the GIS designs of a county in the USA with a county in Germany.