ABSTRACT

This book is destined to serve as a classic reference source to which researchers can turn for a historical perspective and basic information on the physiology, biochemistry, and pathology of the liver. Major areas covered in the book include histological organization, classification of chemical-induced injury, stages of cellular injury, and xenobiotic metabolism. Chapters discussing the use of biochemical methods to determine liver damage, the effects of various chemical agents of the liver, and hepatocarcinogenesis are also presented. Toxicologists, physiologists, physicians, biochemists, industrial hygienists, and others interested in the effects of chemical agents on the structure and function will find this book to be an indispensable source of information.

chapter Chapter 1|65 pages

Structural Organization of the Liver

chapter Chapter 4|42 pages

Xenobiotic Biotransformation

chapter Chapter 8|73 pages

Biochemical Aspects of Fatty Liver

chapter Chapter 11|43 pages

Alcohol-Induced Hepatotoxicity

chapter Chapter 12|44 pages

Mechanisms of Cholestasis