In the fall of 2001, EPA completed publishing a comprehensive guidance document on the bioremediation of marine shorelines and freshwater wetlands (Zhu et al. 2001). Two years later, EPA followed up with a second guidance document devoted exclusively to salt marshes (Zhu et al. 2004). This chapter summarizes both documents by incorporating their salient features in one concise report so that readers do not need to refer to the main documents to extract information important to them. If more detailed explanations are desired, one can always refer back to the original documents.