ABSTRACT

Electrochemical genosensors for the detection of bacteria were

introduced about a decade ago. Miniaturization and advanced

microfabrication technology have made it compatible with bacteria

DNA diagnostic. This technology is cost effective, fast, and accurate.

The bioaffinity and biocatalysis reactions generate amperometric,

voltametric, impedimetric, or conductimetric signals on screen-

printed transducer chips (SPC), which is proportional to the number

of immobilized DNA copies on the SPC surface. Electrochemical

genosensor assays give quantitative rather than qualitative results.

Furthermore, the use of a hand-held portable reader makes this

assay suitable for use in the field, especially for point-of-care (POC)

tests at the patient bedside, during surveillance and environmental

studies of microorganisms.