ABSTRACT
In this chapter, the use of nanoparticles (NPs) in catalytic
electrochemical analysis of DNA as a new detection strategy
reported in recent years is revised. The topics covered here
include labeling with nanoparticles and their subsequent signal
enhancement employed for DNA hybridization detection. Direct
sensing of nanoparticle labels as well as indirect detection routes
through electrochemical sensing of label-catalyzed reactions have
been reported. Nanofabrication of platforms used for the detection
of DNA through electrochemical signal amplification has also
been revised. Some recent examples of interesting nanoparticle-
induced catalytic methodologies applied for protein detection using
electrochemical biosensors are also given, because of their potential
interest in future applications in DNA detection.
