chapter  10
Oxidative stress
ByIrfan Rahman, William MacNee
Pages 20

Biological systems are continuously exposed to oxidants either generated endogenously by metabolic reactions (e.g. from mitochondrial electron transport during respiration or released from phagocytes) or exogenously, such as air pollutants or cigarette smoke. The tissues are protected against this oxidative challenge by welldeveloped enzymatic and non-enzymatic antioxidant defence systems.1