chapter  7
Pretargeted Radioimmunotherapy of Cancer
WithMarco Chinol, Chiara Grana, Roberto Gennari, Marta Cremonesi, J. G. Geraghty, Giovanni Paganelli
Pages 25

A. Introduction Strategies for treating most cancers usually employ surgical resection, chemotherapy, and/or radiation therapy. Although surgical resection can be very effective and sometimes curative in localized tumors, the presence of distant sites or inoperable tumors leaves the options of chemotherapy and/or radiotherapy. If chemotherapeutic drugs or radiotherapy could be selectively delivered to tumors, it would be possible to avoid, or at least reduce, unwanted toxicity and improve efficacy (1).