ABSTRACT

MARCEL G.WUBBOLTS1, CHRISTOPHER BUCKE3 and STANISLAW BIELECKI2

1 DSM Research, P.O. Box 18, NL-6160 MD Geleen, The Netherlands. e-mail: marcel.wubbolts@dsm-group.com

2 Institute of Technical Biochemistry, Lodz Technical University, Stefanowskiego str. 4/10, PL-90-924 Lodz, Poland, e-mail: stanb@ck-

sg.p.lodz.pl 3 School of Biological and Health Sciences, University of Westminster, 115 New

Cavendish Street, London WIM 8JS, United Kingdom. e-mail: buckec@westminster.ac.uk

ABSTRACT Finding a catalyst, be it an isolated enzyme or a whole cell system, for a biocatalyst application is frequently not an easy task. With a desired product in mind, one has to consider variously suited starting compounds, which are preferably commercially available or cheaply synthesized, and the enzymatic steps leading to the products of interest. Furthermore, the chemo-, regio-and stereoselectivity of the biocatalyst towards functional groups of the starting compounds should be taken into account.