ABSTRACT

One of the goals of RNA-based nanotechnology is the development of smart molecules capable of disrupting oncogenic and disease molecular pathways in a selective way. RNA is well suited to combining structural scaffolds and active agents made out of the same building material. Summaries of RNA-based nanotechnology, discussing design and building strategies for RNA nanoscale structures and ideas of their applications in medicine, have been presented in reviews of the field (Guo 2010; Shukla et al. 2011).