ABSTRACT

Harvinder S. Gill The Wallace H. Coulter Department of Biomedical Engineering at Georgia Tech and

Emory University, Georgia Institute of Technology, Atlanta, Georgia, U.S.A.

Jung-Hwan Park Kyungwon University, Seoul, Korea

INTRODUCTION

Transdermal drug delivery is an attractive method of administration drug (1,2). Delivery across the skin circumvents the enzymatic degradation, poor intestinal absorption, and first-pass liver effect associated with oral delivery. It also avoids the pain and inconvenience of injections. In addition, drug delivery across the skin readily lends itself to sustained or modulated delivery from a passive or active patch. For these reasons, transdermal drug delivery represents a multi-billion dollar market, which has significant impact on medical practice.