chapter  8
Food Allergy: Current Diagnostic Methods and Interpretation of Results
ByJohn M. James and A. Wesley Burks, Jr.
Pages 18

As many as 30% of surveyed households in the United States report at least one individual who is thought to be allergic to a food or food ingredient (1). Epidemiological studies using well-controlled food challenges to con rm suspected food allergy, however, have demonstrated a much lower prevalence, 25% of children and less than 2% of adults (2-4). This discrepancy in public

Food Challenges

Food Positive % Positive Reference Population Challenges DBPCFC DBPCFC

Bock 1990 Children 1014 245 24% Sampson 1985 Children with atopic 370 101 27%

dermatitis Jansen 1994 General adult 19 9 47%

Dutch population Host 1990 Danish infants 117 39 33% Bernhisel-Broadbent 1989 Children 130 43 33% Bernhisel-Broadbent 1992 Children 50 15 30%

Young adults

opinion underscores the importance of understanding the diagnostic methods used in the clinical evaluation and con rmation of adverse reactions to foods.