chapter  22
6 Pages

Conversion of Allyl 2-acetamido-2-deoxy-β-d-glucopyranoside to Allyl 2-acetamido-2-deoxy-4,6-di-O-pivaloyl-β-d-galactopyranoside

The biological role of oligosaccharides in cell signaling is well established, and interest in such compounds as therapeutics is growing.1 Therefore, it has become increasingly important to gain access to pure, well-dened, complex carbohydrates. Chemical synthesis is one among the tools to obtain this class of compounds. N-acetyl-d-galactopyranose glycosylated at O-3 is commonly found in natural,

Experimental .......................................................................................................... 174 General Methods ............................................................................................... 174 Allyl 2-acetamido-2-deoxy-3,6-di-O-pivaloyl-β-d-glucopyranoside (2) .......... 174 Allyl 2-acetamido-2-deoxy-4,6-di-O-pivaloyl-β-d-galactopyranoside (3) ....... 175

Acknowledgment ................................................................................................... 175 References .............................................................................................................. 178

physiological and in pathological circumstances.