chapter  1
8 Pages

Synthesis of Higher-Carbon Sugars Using the Phosphonate Methodology: Part I—Synthesis of Methyl (methyl 2,3,4-Tri-O- benzyl-α-d-glucopyranosid)uronate ..................................................... and Sławomir Jarosz

ByGrzegorz Witkowski, Anna Zawisza, Michał Malik

The chiron approach represents a useful methodology in the synthesis of optically pure complex derivatives.1 Synthesis of such targets with numerous hydroxyl groups can be conveniently carried out from sugar chirons. These starting materials are also used for the preparation of compounds possessing wide therapeutic applications such as iminosugars (e.g., nojirimycin).2 Carbohydrate chirons may be also applied

Experimental Methods ...............................................................................................5 General Methods ...................................................................................................5