chapter  18
Medulloblastoma
ByDavid W. Ellison, Steven C. Clifford, Felice Giangaspero
Pages 18

In the World Health Organization (WHO) classification of tumors of the nervous system, the medulloblastoma is placed among embryonal neuroepithelial tumors (Kleihues and Cavanee, 2000). It is a tumor of the cerebellum, and encompasses a morphologically heterogeneous group of neoplasms. This diversity is reflected in distinct sets of molecular abnormalities, which may signify divergent mechanisms of pathogenesis/histogenesis (Ellison, 2002).