ABSTRACT
Technical differences in the two products are less than the similarities. The complex size is as follows:
1. BOTOX® (onabotulinumtoxinA): 900 kDa 2. Dysport® (abobotulinumtoxinA): 500 to 700 kDa 3. Xeomin (oncobotulinumtoxinA): 150 kDa-naked neurotoxin 4. Purtox: 150 kDa-naked neurotoxin
Other differences are in the composition of the product, which is summarized in Table 8A.1 . Protein content is slightly greater in onabotulinumtoxinA with more serum albumin, but the carriers-NaCl and lactose-do differ; whether or not this makes a clinical difference is unknown.
