ABSTRACT

Uterine fibroids or leiomyomas are a common, benign disease of the uterus. The earliest accurate description of uterine fibroids was provided by Reinier De Graff (1641-1673). He described uterine fibroids as sharply circumscribed, firm, white tumors that can vary in size from tiny nodules to large tumors that fill the pelvis. The average affected uterus exhibits six to seven fibroids, which can range in size from 10 mm to over 20 cm (1). Fibroids can be found protruding into the uterine cavity (submucosal), within the uterine wall (intramural), beneath the uterine serosa (subserosal), and in rare instances attached to abdominopelvic structures (parasitic).