chapter  33
8 Pages

Antioxidant Activity in Grape and Other Fruit Extracts Inhibits Peroxynitrite-Dependent Oxidation (from SIN-1) as Measured by Luminescence

A continuous and long-term deficiency in antioxidants is believed to be responsible for the etiology of many diseases,

including the neurodegenerative disorders Alzheimer’s disease, Parkinson’s disease, amyotrophic lateral sclerosis, Huntington’s chorea, as well as a variety of inflammatory diseases such as atherosclerosis, diabetes, arthritis, and the aging process itself. Even diseases such as cancer and certain viral infections are exacerbated by a deficiency in antioxidants. Human papilloma virus (HPV) can cause genital warts, various types of cancer, and is a major risk factor in squamous cell carcinoma. The multiplication and possibly the transformation of HPV is inhibited by high levels of antioxidants, both

in vitro

and

in vivo.