chapter  17
24 Pages

Introduction

WithJulius V. Halaschek-Wiener, Marco A. Marra, Angela R. Brooks-Wilson

Pharmacogenomics combines genomics ;investigations into the structure or function of very large numbers of genes undertaken in a simultaneous fashion, with the study of phenotypes and traits specifically related to drug responses. Gene expression analysis is an important and widely applied genomics tool. Gene expression analyses, either at the single gene level or by means of whole genome approaches, are integral to our understanding of how drugs work, whether they are effective, and whether a subset of the human population will either fail to benefit from a given drug or experience adverse affects from it.