ABSTRACT
Cellular uptake of therapeutic agents requires assistance of agents facilitating the crossing of the natural barrier, which is the plasma membrane. A large number of such agents have been developed in the recent past, mainly devoted to the transfer of nucleic acids and proteins. Among them, peptides appear to be very powerful tools for the transfer of DNAs; two main strategies are concerned: (1) covalent linkage between cargo and vector, thus forming a conjugate, and (2) formation of a complex between the two partners.
