ABSTRACT
By their very nature, traumatic injuries commonly break down our most important barriers to infection: the external skin and endothelium of the gut, lung, and genito-urinary systems. Even in “closed” injuries such as bony fractures or head injuries, many of our supportive and resuscitative therapies violate these barriers, for example, placement of central venous catheters, endotracheal intubation, and surgical repairs. The experienced physician is mindful of the potential harm that may result from invasive interventions, as well as the anticipated benefits.
