chapter  5
Analysis of Nucleic Acids by Mass Spectrometry
ByDirk van den Boom and Franz Hillenkamp
Pages 22

Introduction..............................................................................................................85 The Challenge of MALDI Mass Spectrometry for Oligonucleotide Analysis ......... 86

Sample Purification......................................................................................86 Sample Preparation for MALDI Mass Spectrometry .................................87 Ion Fragmentation........................................................................................88 Instrumentation ............................................................................................89 Quantification and Mixture Analysis ..........................................................90

Role of MALDI-TOF-MS in High-Throughput Sequence Analysis Applications ..........................................................................................90