ABSTRACT

Environmental and economic factors have caused an ambitious shift from organicsolvent-based to water-based film coatings for pharmaceutical dosage forms. The significantly higher heat of vaporization of water has required improved efficiency in coating equipment, such that conversion to aqueous systems can be achieved with a minimum of difficulty. The choice of proper equipment and the creation of a suitable processing environment are as essential to achieving a good film coating as is the selection of the appropriate coating formulation. This is particularly true for aqueous film coating.