chapter  18
14 Pages

Neurologic complications associated with genitourinary cancer

BySamer S. Kasbari, Marc S. Ernstoff, Camilo E. Fadul

INTRODUCTION Genitourinary (GU) malignancies comprise a diverse group of cancers, which have distinct biologic behavior. Although direct or indirect involvement of the nervous system by these tumors usually appears in the setting of advanced neoplastic disease, it varies significantly and in some cases it could be the first manifestation of the disease. Understanding the metastatic patterns will assist the clinician in the evaluation and treatment of patients with neurologic complications from GU malignancies. Because of their low frequency and subtle initial symptoms (Table 1), the clinician should be alert to the possibility of neurologic compromise, since prompt evaluation and treatment will improve patient outcome.