chapter  22
24 Pages

HIV-1 Infection and Cell Death in the Nervous System

Neurological Dysfunction Associated with HIV-1 Infection ........................................................381 HIV-1 Gene Expression in the Nervous System...........................................................................383 Neuronal Cell Death in HIV-1 Infection .......................................................................................383 Direct Effect of Viral Proteins .......................................................................................................384 Soluble Factors from Macrophages/Microglia Exposed to HIV-1 ...............................................386 Distinct HIV-1 Strains and Neurological Disease.........................................................................388 Mechanisms of Neuronal Apoptosis..............................................................................................388