chapter  5
18 Pages

Deadly Intentions: Apoptosis in the Peripheral Immune System

Introduction ......................................................................................................................................77 A View to a Kill-General Mechanisms of Apoptosis ..................................................................77 Outside Influences or an Inside Job-The Extrinsic and Intrinsic Pathways................................80 All Revved Up with No Place to Grow-Activation-Induced Cell Death (AICD) and Peripheral Deletion ...................................................................................................................81 Murder by Proxy-Nonlymphoid Cells in Peripheral Lymphocyte Deletion ...............................84 In the Company of Killers-Induction of Apoptosis by Cytotoxic Lymphocytes ........................85 Summary ..........................................................................................................................................86 References ........................................................................................................................................87