chapter  5
28 Pages

Carbon Monoxide, Vascular Contractility, and K+ Channels

I. Introduction..................................................................................................83 II. Roles of Various K

Channels in Regulation of the Functions of Vascular SMCs ........................................................................................84 A. The Coupling of Membrane Potential Change

to SMC Contraction — The Role of K

Channels ............................84 B. The Coupling of Intracellular Calcium Change

to SMC Contraction — The Role of K

Channels ...........................85 C. The Coupling of Cellular Metabolic Change

to SMC Contraction — The Role of K

Channels..........................86 III. Molecular Basis of K

Channels .................................................................89 A. K

Channels ........................................................................................89 B. K

Channels .......................................................................................91 C. K

Channels......................................................................................93 IV. The Effects of CO on K

Channels in Vascular SMCs ..............................95 A. The Effects of CO on K

Channels in Vascular SMCs and Other Types of Cells ....................................................................96