chapter  8
10 Pages

Extended Activity of Healthcare Antiseptic Products

WithJerry L. Newman, Nancy E. Kaiser

CONTENTS 8.1 Introduction ............................................................................................... 155 8.2 Effects (or Activity)................................................................................... 156 8.3 Modes of Action........................................................................................ 158 8.4 Surgical Hand Scrubs............................................................................... 160 8.5 Patient Surgical Skin Preparations......................................................... 160 8.6 Healthcare Personnel Handwash........................................................... 160 8.7 Summary .................................................................................................... 161 References ........................................................................................................... 162

The extended activity of antiseptic agents has been studied for many years. The literature describing extended activity uses many terms and these terms have been used interchangeably and with little discrimination, based on mechanisms or effects. Examples of this term proliferation in the literature can often be found within the same paper. As well as being confusing, this practice has served to potentially diminish the perception of the benefit of such effects. Persistent, residual, and cumulative are the terms most commonly used to describe extended activity. These three terms have been applied somewhat indiscriminately to different active agents, which have different modes of action and different use classifications. There is therefore confusion as to whether these words describe differentiated characteristics of extended activity or modes of action. However, some clarity can be achieved by looking at the terms with a systematic approach based on standards for English terminology and most common use patterns.